Frontline Top Spot for Cats

How does it work?
What precautions should I take?
Where can I get it cheap?

How Does it Work?

The active ingredient in Frontline Top Spot is called "fipronil." It's a topical flea insecticide that works by getting into the oils of your cat's skin and hair follicles.

It kills adult fleas and many types of ticks in cats and kittens, including deer ticks, which is the major carrier of Lyme disease.

This flea eliminator works by killing newly hatched adult fleas before they have a chance to lay flea eggs. This breaks the flea life cycle and helps get rid of all fleas. 

Fipronil continues to work even if your cat gets wet or is exposed to sunlight. 

How Long Does it Take to Work?

This flea medicine kills fleas shortly after the parasite comes into contact with your cat's skin. There is no need for it to bite your cat for it to work. 

This insecticide kills fleas and ticks for at least one month. 

How to Apply Frontline Top Spot for Cats

Here are the steps to properly apply this topical solution. The directions come directly from the manufacturer's instructions.

Frontline Top Spot for CatsFrontline Top Spot for Cats
  1. Remove applicator from child-resistant package.
  2. Hold applicator upright and snap applicator tip away from face and body.
  3. Place applicator tip through animal's hair to the skin level between the shoulder blades.
  4. Squeeze applicator, applying entire contents to a single spot to the animal's skin.
  5. Avoid superficial application to the animal's hair.
  6. Only one applicator per treatment is needed.

Safe for Kittens (but Be Careful)

According to the product label at the manufacturer's web site, Top Spot can be used on kittens 12 weeks and older. This is a little strange, since the product label for Frontline Plus says not to use on kittens under 8 weeks of age. 

Frontline Top Spot contains 9.7% of the active ingredient fipronil, while Frontline Plus contains 9.8% of this flea insecticide, and 11.8% of methoprene. 

It's probably safest to consult your veterinarian when using any Frontline product for kittens, or use Advantage Flea Control, which is safe for kittens as young as 8 weeks old. 


The area where you apply this flea killer may appear wet or oily for up to 24 hours after application. This is normal, but don't touch the area until dry.

If you accidentally touch the area, be sure to thoroughly wash your hands with soap and water. 

Possible Dangers

According to the product label, "individual sensitivities, while rare, may occur after using any pesticide product for pets. Pets may experience some temporary irritation at the site of product application. If signs persist, or become more severe within a few days of application, consult a veterinarian immediately. Certain medications can interact with pesticides. Consult a veterinarian before using on medicated animals. Consult a veterinarian before using this product with other pesticides. This product may be harmful to debilitated, aged, pregnant, or nursing animals; consult a veterinarian before using." 

No Prescription Required

Frontline flea control products are now available without a prescription. You can buy Frontline Top Spot in 3, 6, and 12 dose packages directly from many pet supplies stores and discount pet supplies stores online.

Top Recommendation for Discount Flea Medication Online

For transparency and disclosure, you should assume that all links on this page are affiliate links and that I do receive a commission if you click through and make a qualifying purchase.

That said, please note that I only recommend products that I believe in.

Amazon carries this flea medication and all the other popular flea control medications at a steep discount. 

Only Natural Pet Store is my #1 recommendation for natural flea control products. If you decide to go natural, this is the place to go.

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